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Desarrollo diferencial del cuerpo calloso en relación con el hemisferio cerebral

Authors: Quintero Gallego, Eliana Alexey; Manaut Gil, Enrique; Rodríguez Martínez, Elena Isabel; Pérez Santamaría, Francisco Javier; Gómez González, Carlos María;

Desarrollo diferencial del cuerpo calloso en relación con el hemisferio cerebral

Abstract

El Cuerpo Calloso (CC) es una de las principales comisuras interhemisféricas en el hombre. Hoy en día, se ha enriquecido el conocimiento existente sobre la función y estructuras cerebrales in vivo. En el presente estudio, de tipo retrospectivo, se han tomado 72 placas de Resonancias Magnéticas Nucleares (RMN) en cortes sagitales, de una muestra de niños y jóvenes adultos de edades comprendidas entre los 6 meses y 21 años (32 niños y 40 niñas). Nuestro objetivo consistió en estudiar el patrón de la evolución morfológica del CC en relación con el crecimiento hemisférico en su vista lateral. Esta relación se midió mediante la razón del área hemisférica dividida por el área del CC (I h/cc). Para los análisis estadísticos se utilizaron estadísticas no paramétricas. La prueba H de Kruskall- Wallis mostró diferencias significativas entre los grupos de edad. Utilizando la U de Mann-Whitney se observó que dichas diferencias se encontraban entre los grupos más pequeños respecto a los grupos de niños con mayores edades. La tendencia observada en nuestros datos muestra cambios más drásticos en los primeros grupos (es decir, hasta los 4 años), con una estabilización en edades posteriores. Esto sugiere un mayor crecimiento del CC en relación con el hemisferio en edades tempranas (hasta los 4 años) con una estabilización a partir de los 7 años. Este incremento en el área del CC puede estar relacionado con la mielinización de las fibras de conexión interhemisféricas.

The Corpus Callosum (CC) is one of the main interhemispheric comissures in man. Using modern neuroimaging techniques it has been possible to study the brain morphology and the relationship structure- function in vivo. In this retrospective study we took 72 Magnetic Resonance Imaging (MRI) images of the middle sagital plane from children and young adults whose ages were from 6 months to 21 years (32 boys and 40 girls). Our goal was to study the pattern of the morphologic evolution of the CC with respect to the hemispheric growth in its middle sagital view. We computed this relation by dividing the hemispheric area by the corpus callosum area (I h/cc). For the statistical analyses, nonparametric statistics were used. The Kruskall- Wallis test showed significant differences between the averages of I h/cc of the different group ages. Using the U of Mann-Whitney test, it was observed that the differences were due to differences between the young boys (until the age of 4) with respect to the older children (after 7). This results suggests a faster growth of the CC in relation to the growth of the hemisphere in early ages (until the 4 years) with a stabilization of relative growth around the age of 7. This increase in the area of the CC could be related with the mielinization of connection fibers.

Country
Spain
Related Organizations
Keywords

Cuerpo calloso, Desarrollo diferencial, Corpus callosum, Differential development, Cerebral hemispheres, Hemisferios cerebrales

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
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