
handle: 11441/64253
La leucoplasia es un desorden potencialmente maligno que se da con una prevalencia relativamente alta a nivel mundial. Dado el riesgo de transformación maligna que posee, son necesarios un diagnóstico precoz y un tratamiento efectivo temprano. Actualmente, las opciones de tratamiento para este tipo de patología se basa fundamentalmente en la extirpación quirúrgica con márgenes de seguridad, lo que supone un procedimiento traumático para el paciente, unas secuelas en algunos casos importantes y un pronóstico impredecible al depender éste de la escisión completa de todo el tejido involucrado en la lesión. Estos factores determinan el alto ratio de recidivas, ya que no son fácilmente controlables. Debido a todo esto, la búsqueda de nuevas alternativas más precisas y menos invasivas es crucial. Las opciones aquí revisadas son la terapia fotodinámica, la crioterapia, el licopeno, la talidomida y los retinoides.
The oral leukoplakia is a potentially malignant disorder that occurs with a relatively high prevalence worldwide. Given the high risk of malignant transformation, an early diagnosis and effective treatment are necessary. Currently, the treatment options for this type of pathology is mainly based on surgical excision margins, which is a traumatic procedure for the patient, with important consequences in some cases and an unpredictable prognosis, as this depends on the complete excision of all the involved pathological tissue. These factors determine the high rate of recurrence, as they are not easily controlled clinically. Because of all this, the search for new, more accurate and less invasive alternatives is crucial. The options revised here are photodynamic therapy, cryotherapy, lycopene, thalidomide and retinoids.
Universidad de Sevilla. Grado en Odontología
Leucoplasia oral
Leucoplasia oral
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