
We describe here the clinical applications of fluorescence in situ hybridization(FISH) in patients with chronic myelogenous leukemia under treatment with interferon-alpha, some cases with a false positive caused by preparation of specimen and/or probes, and the detection of chimerism after sex-mismatched bone marrow transplantation based on our clinical experience. Furthermore, we introduced our methods of performing FISH using blood smear or G banding specimens.
Transplantation Chimera, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Humans, Interferon-alpha, False Positive Reactions, In Situ Hybridization, Fluorescence, Bone Marrow Transplantation
Transplantation Chimera, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Humans, Interferon-alpha, False Positive Reactions, In Situ Hybridization, Fluorescence, Bone Marrow Transplantation
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