In this paper we study general protocell models aiming to un-derstand the synchronization phenomenon of genetic material and containerproductions, a necessary condition to ensure sustainable growth in protocellsand eventually leading to Darwinian evolution when applied to a populationof protocells.Synchronization has been proved to be an emergent property in many rel-evant protocell models in the class of the so–called Surface Reaction Models,assuming both linear and nonlinear dynamics for the involved chemical reac-tions.