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Inhibidors de la bomba de protons i dèficit de vitamina B12

Inhibidors de la bomba de protons i dèficit de vitamina B12

Abstract

Aquest informe analitza l’augment del consum d’inhibidors de la bomba de protons (IBP) i la seva relació amb el dèficit de vitamina B12. Així doncs, la hipòtesi plantejada és la següent: d’una banda, s’hauria d’observar una prevalença més alta d’ús d’IBP en pacients tractats amb AINE, anticoagulants, antiagregants o corticoides. I de l’altra, Si els IBP augmenten el risc de dèficit de vitamina B12, s’hauria de registrar una elevada incidència de nous tractaments amb vitamina B12 en els mesos següents. Aquest informe analitza l'augment en el consum d'inhibidors de la bomba de protons (IBP) i la seva relació amb el dèficit de vitamina B12. En aquest context, la hipòtesi plantejada és la següent: d'una banda, s'hauria d'observar una prevalença més alta en l'ús d'IBP entre els pacients que reben tractament amb antiinflamatoris no esteroïdals (AINE), anticoagulants, antiagregants o corticoides. D'altra banda, si els IBP augmenten el risc de dèficit de vitamina B12, s'hauria de registrar una incidència elevada de nous tractaments amb vitamina B12 durant els mesos posteriors.

Este informe analiza el aumento del consumo de inhibidores de la bomba de protones (IBP) y su relación con el déficit de vitamina B12. En este contexto, la hipótesis planteada es la siguiente: por un lado, se debería observar una prevalencia más alta en el uso de IBP entre los pacientes que reciben tratamiento con antiinflamatorios no esteroides (AINE), anticoagulantes, antiagregantes o corticoides. Por otro lado, si los IBP aumentan el riesgo de déficit de vitamina B12, se debería registrar una incidencia elevada de nuevos tratamientos con vitamina B12 durante los meses posteriores.

This report analyzes the increase in the consumption of proton pump inhibitors (PPIs) and their relationship with vitamin B12 deficiency. In this context, the proposed hypothesis is as follows: on the one hand, a higher prevalence of PPI use should be observed among patients receiving treatment with non-steroidal anti-inflammatory drugs (NSAIDs), anticoagulants, antiplatelets, or corticosteroids. On the other hand, if PPIs increase the risk of vitamin B12 deficiency, a higher incidence of new treatments with vitamin B12 should be recorded in the following months.

Inhibidores de la bomba de protones; Déficit vitamina B12

Inhibidors de la bomba de protons; Dèficit vitamina B12

Proton pump inhibitors; Vitamin B12 deficiency

Keywords

DISEASES::Nutritional and Metabolic Diseases::Nutrition Disorders::Malnutrition::Deficiency Diseases::Avitaminosis::Vitamin B Deficiency::Vitamin B 12 Deficiency, ENFERMEDADES::enfermedades nutricionales y metabólicas::trastornos nutricionales::desnutrición::enfermedades carenciales::avitaminosis::deficiencia de vitamina B::deficiencia de vitamina B12, Medicaments gastrointestinals - Prescripció, COMPUESTOS QUÍMICOS Y DROGAS::acciones y usos químicos::acciones farmacológicas::mecanismos moleculares de acción farmacológica::inhibidores enzimáticos::inhibidores de la bomba de protones, CHEMICALS AND DRUGS::Chemical Actions and Uses::Pharmacologic Actions::Molecular Mechanisms of Pharmacological Action::Enzyme Inhibitors::Proton Pump Inhibitors

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
Green