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Article . 2008
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Histopathological Lesions on central nervous system intoxication of goats by Ipomoea carnea spp fistulosa (Convolvulácea)

Authors: Ríos, E.; Cholich, Luciana Andrea; Silva, J.; Acosta de Pérez, O.;

Histopathological Lesions on central nervous system intoxication of goats by Ipomoea carnea spp fistulosa (Convolvulácea)

Abstract

Ipomoea carnea var. fistulosa (Convolvulaceae) es una planta tóxica, perenne, distribuida en el nordeste de Argentina. La intoxicación produce una enfermedad de almacenamiento lisosomal en cabras, ovejas y bovinos. Cinco cabras fueron tratadas vía oral con 50g/kg/ día de hojas frescas, flores y tallos de I. carnea, durante 43–60 días. En todos los animales tratados se observó pelo hirsuto, depresión, dificultad en la estación, ataxia, hipermetría, aumento de la base de sustentación, incoordinación de movimientos, intensos tremores, paresia espástica, reacciones posturales anormales, nistagmo, hiperreflexia, hipersensibilidad a los sonidos, cabeza inclinada y pérdida de equilibrio. El estudio histopatológico reveló la presencia de vacuolización citoplasmática principalmente en medula oblonga y cerebelo. Los animales controles no mostraron anormalidades. Se concluye que la intoxicación por I. carnea provoca daños en el sistema nervioso central, resultando las células de Purkinje las más severamente afectadas más severamente afectadas

Ipomoea carnea var. fistulosa (Convolvulaceae) is a perenne poisonous plant, found throughout the Argentine Northeastern. The intoxication produces a lysosomal storage disease in goats, sheep and cattle. Five goats were fed with 50 g/kgBW/day of fresh leaves, flowers and stems of I. carnea, during 43–60 days. Hirsute coat, depression, difficulty to stand up, ataxia, hypermetria, wide–based stance, incoordination of muscular movements, intense tremors, spastic paresis, abnormal postural reactions, nystagmus, hyperreflexia, hypersensitivity to sound, head tilting and loss of equilibrium were observed in all treated animals. The histopathologic study revealed the presence of cytoplasmatic vacuolation mainly in medulla oblongata and cerebellum. Control animals did not show any alterations. We conclude that this poisoning causes central nervous system damage, being Purkinje cells the most severely affected

Fil: Cholich, Luciana Andrea. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional del Nordeste. Facultad de Ciencias Veterinarias; Argentina

Fil: Acosta de Pérez, O.. Universidad Nacional del Nordeste. Facultad de Ciencias Veterinarias; Argentina

Fil: Silva, J.. Universidad Nacional del Nordeste. Facultad de Ciencias Veterinarias; Argentina

Fil: Ríos, E.. Universidad Nacional del Nordeste. Facultad de Ciencias Veterinarias; Argentina

Country
Argentina
Keywords

intoxicación, INTOXICATION, IPOMOEA CARNEA, cabra, https://purl.org/becyt/ford/4.3, GOAT, https://purl.org/becyt/ford/4, NERVOUS SYSTEM LESIONS, lesiones sistema nervioso

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
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