Powered by OpenAIRE graph
Found an issue? Give us feedback
downloadFull-Text
image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ LAReferencia - Red F...arrow_drop_down
image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
LAReferencia - Red Federada de Repositorios Institucionales de Publicaciones Científicas Latinoamericanas
Article . 2015
License: CC BY NC ND
Full-Text: https://www.journalajst.com/diclofenac-sodium-uv-degradation
Data sources: LAReferencia - Red Federada de Repositorios Institucionales de Publicaciones Científicas Latinoamericanas
image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
LAReferencia - Red Federada de Repositorios Institucionales de Publicaciones Científicas Latinoamericanas
Article . 2015
License: CC BY NC SA
Data sources: LAReferencia - Red Federada de Repositorios Institucionales de Publicaciones Científicas Latinoamericanas
image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
CONICET Digital
Article . 2015
License: CC BY NC SA
Data sources: CONICET Digital
 View all 4 versions
Claim

Diclofenac Sodium UV degradation

descriptionPublicationkeyboard_double_arrow_right Article 01 Jul 2015 Argentina English Publisher:Asian Journal of Science and Technology Publishers
Authors: Ruiz, Jimena; Delfino, Mario Raul; Monzón, Celina María; Jorge, Nelly Lidia; Sarno, María del Carmen Teresa;

handle: 11336/44749

Diclofenac Sodium UV degradation

Abstract

Diclofenac sodium (2- [2 - [(2,6-dicloro-fenil) amino] phenyl] sodium acetate) is an nonsteroidal antiinflammatory drug widely used today as an analgesic, anti-arthritic and anti-rheumatic. It is susceptible to stress caused by UV radiation. In this work photodegradation of diclofenac was monitored in batch mode using a photolysis orthogonal chamber. Diclofenac aqueous solutions of pH 9 were subjected to the effect of UV radiation of 254nm from a mercury lamp UVP with wood glass, located at 15 cm from the liquid surface. UV Spectra of solutions exposed for periods of time in the range of 5 minutes to 48 h were scanned. Diclofenac molecule without UV treatment exhibits a maximum at 195 nm and another at 276 nm. At very short treatment times a peak appears around 239 nm, where in the original molecule the absorbance is minimal. Another peak begins to emerge at 289 nm, which becomes more apparent at times of treatment longer than 1 hour. Simultaneously in greater times peaks at 225 and 250 nm appear. The absorptiometric measurements were complemented by the application of quantum theoretical chemistry using the static approximation and density functional theory, B3LYP. The excitations energies B3LYP for diclofenac and for the photolysis products are closed with the experimental measurements. Based on this, a mechanism for the reaction of photolytic degradation of diclofenac in the tested conditions is proposed.

Fil: Sarno, María del Carmen Teresa. Universidad Nacional del Nordeste. Facultad de Ciencias Exactas Naturales y Agrimensura; Argentina.

Fil: Monzón, Celina María. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico; Argentina.

Fil: Delfino, Mario Raúl. Universidad Nacional del Nordeste. Facultad de Ciencias Exactas y Naturales y Agrimensura; Argentina.

Fil: Delfino, Mario Raúl. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico; Argentina.

Fil: Monzón, Celina María. Universidad Nacional del Nordeste. Facultad de Ciencias Exactas Naturales y Agrimensura; Argentina.

Fil: Jorge, Nelly Lidia. Universidad Nacional del Nordeste. Facultad de Ciencias Exactas Naturales y Agrimensura; Argentina.

Fil: Ruiz, Jimena. Universidad Nacional del Nordeste. Facultad de Ciencias Exactas Naturales y Agrimensura; Argentina.

Country
Argentina
Related Organizations
Keywords

Diclofenac, Uv Radiation, Photodegradation, https://purl.org/becyt/ford/1.4, Quantum Theoretical Chemistry, Quantum theoretical chemistry, https://purl.org/becyt/ford/1, UV radiation

  • BIP!
    Impact byBIP!
    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 0
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 Average
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    		 Average
Powered by OpenAIRE graph
Found an issue? Give us feedback
selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
Green