The present work faces the issue of energetic quality in architecture, aiming in particular at analyzing the new and unexplored opportunities new generation insulation materials seem to offer. A focus is made on the use of multifoil insulations, considered among the most advanced materials within building insulation products market, to guarantee the best possible ratio between costs and performances according to the overall thickness of the analyzed solutions. Particularly, the paper deals with the use of these materials within ventilated wall systems and the evaluation of the consequent performances and practical advantages. The study has led to the development of advanced technological solutions suitable to combine a very high thermal performances with the integration of solar gain systems (PV, thermal, etc.) for clean energy production, starting from a minimum of only 75 mm. The goal is to introduce a strongly innovative practice within the field of architectural and energetic refurbishment of existing buildings, through the proposal of an advanced envelope technology as an alternative to traditional systems.