
handle: 11311/524137 , 11697/2479
We describe the first synthesis of enantiomerically pure (S)-a-vinyl and (S)-a-ethynyl 3,3,3-trifluoro alanine (TF-Ala) ethyl esters, starting from the in situ generated sulfinimine (S)-2 as key fluorinated building-block. (S)-a-Ethyl TF-Ala-OEt has been prepared as well by this route.
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