Some important questions concerning the pathogenetical mechanisms of the so-called primary-generalized epileptic seizures are discussed. Reviewing the large literary material and personal clinical experience, the author attracts attention of neurologists and psychiatrists to the necessity of very thorough and detailed anamnestic data and eventual neurological observations, in order to detect a focal onset of a generalized seizure. This is very important bor purposes of clinical practice, especially from the standpoint of indications for neurosurgical operations.