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Universiteit van Amsterdam (UvA) Institutional Repository UvA-DARE
Doctoral thesis . 2013
Data sources: Universiteit van Amsterdam (UvA) Institutional Repository UvA-DARE
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Acquired TTP: ADAMTS13 meets the immune system

descriptionPublicationkeyboard_double_arrow_right Doctoral thesis 01 Jan 2013 English
Authors: Sorvillo, N.;

handle: 11245/1.397359

Acquired TTP: ADAMTS13 meets the immune system

Abstract

Autoantibodies directed against ADAMTS13 prohibit the processing of VWF multimers, initiating a rare and life-threatening disorder called acquired thrombotic thrombocytopenic purpura (TTP). At present it is not clear why previously healthy individuals develop anti-ADAMTS13 antibodies. The studies described in this thesis aim to increase our understanding of the molecular mechanisms involved in the generation of anti-ADAMTS13 antibodies in patients with acquired TTP.

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
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