Tuberculosis mortality is 9.3 times higher in men than in women. Women more commonly recover and less frequently die from progressive tuberculosis. The main causes of death are fibrocavernous or infiltrative tuberculosis, and caseous pneumonia. In young people, the most common cause of death is tuberculosis of the meninga or central nervous system, women more frequently die from caseous pneumonia. Prisoners more commonly die from infiltrative tuberculosis and more rarely from fibrocavernous tuberculosis than the general population of Sverdlovsk. The most common causes of death of patients with tuberculosis who die in the first year of its diagnosis are caseous pneumonia and fibrocavernous tuberculosis. The factors predisposing to poor prognosis were late detection of the disease, treatment refusal, severe concomitant diseases, and intolerance of antituberculous agents.