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Genetics. Reprogramming X inactivation.

Authors: P, Clerc; P, Avner;

Genetics. Reprogramming X inactivation.

Abstract

Inactivation of one of the two X chromosomes occurs in all cells of female adult mice so that genes are expressed from only one X chromosome. In a Perspective, Clerc and Avner describe an elegant series of experiments in mouse embryos cloned from adult and embryonic female cell nuclei (Eggan et al.) that reveal how the inactivation state of the X chromosomes is reprogrammed.

Related Organizations
Keywords

Male, Nuclear Transfer Techniques, RNA, Untranslated, X Chromosome, Cloning, Organism, Placenta, DNA Methylation, Embryo, Mammalian, Histones, Embryonic and Fetal Development, Genomic Imprinting, Mice, Dosage Compensation, Genetic, Animals, Female, RNA, Long Noncoding, Transgenes, Transcription Factors

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    Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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Powered by OpenAIRE graph
Found an issue? Give us feedback
selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
11
Average
Top 10%
Top 10%
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