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Repository of the Czech Academy of Sciences
Patent . 2023
Data sources: Repository of the Czech Academy of Sciences
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Repository of the Czech Academy of Sciences
Patent . 2023
Data sources: Repository of the Czech Academy of Sciences
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Claim

Compounds for inhibition of fibroblast activation protein

descriptionPublicationkeyboard_double_arrow_right Patent 06 Apr 2023 Czech Republic English
Authors: Šimková, A. (Adéla); Šácha, P. (Pavel); Sidej, N. (Natan); Ormsby, T. (Tereza); Konvalinka, J. (Jan);

handle: 11104/0349428 , 11104/0349645

Compounds for inhibition of fibroblast activation protein

Abstract

This invention provides quinolinecarboxamide compounds of general formula I which by far exceed the previously known FAP inhibitors in affinity and inhibitory effect. These agents can be used to specifically target tumours for diagnostic and therapeutic purposes, or for laboratory purposes in the study of endogenous FAP expression.

Country
Czech Republic
Related Organizations
Keywords

FAP, protease, inhibition

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
Green