Soubor vzájemně rozlišitelných nanočástic, způsob jejich přípravy a jejich použití pro vícenásobné ultrastrukturální značení

descriptionPublicationkeyboard_double_arrow_right Patent 18 Dec 2013 Czech

Authors: Hozák, P. (Pavel); Šlouf, M. (Miroslav); Nebesářová, J. (Jana); Moša, M.; Krivjanská, M.;

handle: 11104/0232436

Soubor vzájemně rozlišitelných nanočástic, způsob jejich přípravy a jejich použití pro vícenásobné ultrastrukturální značení

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Abstract

The invention relates to a set of nanoparticles with different sizes, shapes and/or elemental composition that can be used for simultaneous highly sensitive immunolabeling of three or more antigens in biological structures. The invention enables detailed analysis of the labelled antigens distribution and interactions within biological structures by means of electron microscopy. The invention includes synthesis of the nanoparticles, their conjugation to biological targeting molecules, and the way of their use in multiple immunolabeling.

Related Organizations

Academy of Sciences Library
Czech Republic

Keywords

imunoznačení, elektronová mikroskopie, nanočástice

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