
handle: 11104/0206237
Lincomycin derivatives are produced by biotechnological cultivation of Streptomyces lincolnensis ATCC 25466 with at least one gene of the 4-L-propylproline biosynthesis coding cluster inactivated. A substitute of the component whose synthesis is blocked by inactivation is added to the medium. In this way new, biologically active lincomycin derivatives are produced biosynthetically
Lincomycin, Streptomyces lincolnensis ATCC 25466
Lincomycin, Streptomyces lincolnensis ATCC 25466
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