Ocular cicatricial pemphigoid is a systemic disease of autoimmune etiology, belonging to the category of acquired oculo-muco-cutaneous bullous dermatosis. Although it is a disease primarily involving the conjunctiva, it frequently affects other mucous membranes (oropharynx, genitalia, anus), and the skin is involved as well in approximately 15% of the cases. The ocular manifestations, during the acute stage, consist of conjunctival bullous, which quickly lead to ulcerous lesions. During the chronic stage the disturbances of the palpebral statics and dynamics, ocular dryness syndrome and corneal lesions will develop. Being a relative less frequent disease, the observation of 3 patients is presented.