This report begins with an Executive Summary, which introduces the territorial development approach and the rationale for applying it in Lesotho’s development context before going on to summarize key takeaways and recommendations. It is followed by four chapters: chapter 1, Introduction, lays out the country context, presenting in brief Lesotho’s economic and demographic situation, population projections, governmental structure, and poverty profile and the government’s goals. Chapter 2, territorial development framework and analysis in Lesotho, discusses the territorial development approach, its objectives, and the challenges it aims to address before presenting a customized 2 by 2 territorial framework for Lesotho and explaining how it can be applied. Chapter 3, analyzing Lesotho’s Challenges through a Territorial Lens, lays out a spatial analysis centering on four development challenges: economic opportunities, internal connectivity and regional integration, access to basic services, and climate preparedness. To highlight the challenges, the chapter includes 4D heat maps linked to density, distance, disparity, and disaster risk. It also summaries case studies and real-life applications of the territorial development approach in Lesotho. Full case studies are in an annex. Chapter 4, recommendations, covers guiding principles and recommendations based on the territorial development approach and analysis.