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Golimumab en la espondilitis anquilosante. Revisión sistemática.

Authors: López Rosa, Juan Jesús;

Golimumab en la espondilitis anquilosante. Revisión sistemática.

Abstract

La espondilitis anquilosante (EA) es una enfermedad reumática inflamatoria de evolución crónica que afecta fundamentalmente al esqueleto axial (tórax, columna vertebral y pelvis), siendo la presencia de sacroileítis el hallazgo radiológico característico. El objetivo de los tratamientos actuales, consiste en reducir al mínimo la actividad inflamatoria de la enfermedad, que mejore los signos y síntomas como inflamación articular, dolor, rigidez, y preserve la capacidad funcional manteniendo la calidad de vida del paciente. Se realizó una búsqueda bibliográfica de la literatura científica existente en las bases de datos Medline, PEDro, Cochrane, ScienceDirect y SCOPUS. Se incluyeron los ensayos clínicos aleatorizados con un máximo de 10 años de antigüedad disponibles a texto completo en lengua inglesa o española con una puntuación de al menos 5 en la escala PEDro.

Ankylosing spondylitis (AS) is a chronic course inflammatory rheumatic disease that primarily affects the axial skeleton (thorax, spine and pelvis), the presence of sacroiliitis the characteristic radiographic finding. The aim of current treatments is to minimize the inflammatory disease activity, improve the signs and symptoms such as joint swelling, pain, stiffness, and preserve the functional capacity while maintaining the quality of life of patients. A literature research was conducted in Medline, PEDro, Cochrane, ScienceDirect and SCOPUS database. This study included Randomized clinical trials with more than 10 years old and available in full text in English or Spanish with a score of at least 5 on the PEDro scale.

Keywords

Clinical Pathology, 3201.04, Ciencias Médicas, Patología clínica, Clinical Sciences, Life Sciences, Ciencias de la vida, 32, 24

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
Green