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Stalk dynamics and lipid flow upon membrane hemifusion.

Authors: D A, Kumenko; P I, Kuzmin; Y A, Chizmadzhev;

Stalk dynamics and lipid flow upon membrane hemifusion.

Abstract

A hydrodynamic theory describing the stalk dynamics and lipid flows upon BLM hemifusion was developed. The value of intermonolayer viscosity, etar, for membranes formed from azolectin mixed with lysophosphatidylcholine (7.10(-4) mg/ml) in n-decane, etar approximately 10(-9) g/s, was determined from comparison of the theoretical calculations and literature data. For membranes formed in squalene, the values etar approximately 10(-7) g/s for phosphatidylethanolamine and etar approximately 2-10(-7) g/s for azolectin were obtained. The calculated values are close to the published results of independent experiments which shows that the developed theory describes well the stalk growth and lipid flow.

Related Organizations
Keywords

Cell Fusion, Membrane Lipids, Nonlinear Dynamics, Cell Membrane, Hydrostatic Pressure, Energy Metabolism, Models, Biological

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
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