
The heparin-neutralizing platelet factor (PF4) is released from platelets under the influence of inducers of aggregation and nucleotide-release in the form of a high-molecular weight complex. The heparin-neutralizing activity is carried by a basic protein of molecular weight 29,700, four of which combine with a proteoglycan carrier, which in turn consists of 4 chondroitin sulfate A residues and a peptide moiety.
Blood Platelets, Chemical Phenomena, Platelet Aggregation, Chemistry, Physical, Protein Conformation, Heparin Antagonists, Blood Coagulation Factors, Rats, Molecular Weight, Organoids, Animals, Humans
Blood Platelets, Chemical Phenomena, Platelet Aggregation, Chemistry, Physical, Protein Conformation, Heparin Antagonists, Blood Coagulation Factors, Rats, Molecular Weight, Organoids, Animals, Humans
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