Powered by OpenAIRE graph
Found an issue? Give us feedback
image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Biblioteca Digital -...arrow_drop_down
image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
Biblioteca Digital - Universidad Icesi
Bachelor thesis . 2018
License: CC BY NC ND
versions View all 1 versions
addClaim

Estudio "in vitro" de la cinética de hinchamiento y liberación de venlafaxina a partir de hidrogeles de quitosano utilizando genipina como agente reticulante

Authors: Villa Castro, Ingrid Tatiana;

Estudio "in vitro" de la cinética de hinchamiento y liberación de venlafaxina a partir de hidrogeles de quitosano utilizando genipina como agente reticulante

Abstract

En el estudio de la cinética de liberación de venlafaxina HCl a partir de los hidrogeles de quitosano/genipina, se obtuvo que los materiales cargados con 37,5 mg se ajustaron al modelo cinético de Korsmeyer-Peppas, mientras que aquellos cargados con 75 mg se ajustaron a un mecanismo de liberación de difusión “Fickiana“. Además, se determinó la uniformidad de contenido en los hidrogeles, arrojando una cantidad de fármaco de 1,3217 mg y 1,3226 mg para las concentraciones comerciales de 37,5 mg y 75 mg de venlafaxina HCl, respectivamente. Por último, se evidenció una liberación lenta de venlafaxina HCl a partir de los hidrogeles con mayor concentración de fármaco, comportándose como vehículos de liberación prolongada para este fármaco que posee un tiempo de vida media corto

Country
Colombia
Related Organizations
Keywords

Quitosano, Cinética, In vitro, Hidrogel, Departamento de Ciencias Farmacéuticas, Genipina, Trabajos de grado, Química Farmacéutica, Venlafaxina

  • BIP!
    Impact byBIP!
    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    0
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Average
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Average
Powered by OpenAIRE graph
Found an issue? Give us feedback
selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
Green