
The cycloferon efficacy was investigated in the treatment of experimental herpesvirus kerato-conjunctivitis in rabbits. The model was demonstrated to reflect the main aspects of herpesvirus eye lesions in humans. Cycloferon application similarly to that of known interferon inducer poludan has been shown to enhance processes of inflammation and subsequent regeneration of eye tissues as well as to decrease mortality of animals due to the generalization of infection.
Interferon Inducers, Time Factors, Drug Evaluation, Preclinical, Keratitis, Herpetic, Acridines, Animals, Simplexvirus, Rabbits, Iridocyclitis, Polyribonucleotides
Interferon Inducers, Time Factors, Drug Evaluation, Preclinical, Keratitis, Herpetic, Acridines, Animals, Simplexvirus, Rabbits, Iridocyclitis, Polyribonucleotides
| selected citations These citations are derived from selected sources. This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | 0 | |
| popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network. | Average | |
| influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | Average | |
| impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network. | Average |
