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handle: 10902/8759
Los trastornos de la conducta alimentaria son un conjunto de síndromes con una incidencia importante que afectan típicamente a mujeres jóvenes, mayoritariamente en edad puberal. Son originados a partir de una compleja etiología multifactorial en la que además de los factores sociales, culturales o personales, están adquiriendo gran importancia las alteraciones biológicas, dentro de las cuales, un grupo cada vez más importante son las alteraciones inmunitarias, a raíz de la demostración de estas en otros trastornos psiquiátricos. En el presente documento se realiza una revisión sistemática a fin de establecer si realmente existe implicación de la respuesta inmune innata, más concretamente de las citoquinas proinflamatorias en los trastornos de la conducta alimentaria, considerando que un mayor conocimiento en este campo puede ayudarnos a comprender mejor este tipo de afectaciones al tiempo que nos permite plantearnos futuras dianas terapéuticas con las que poder combatirlas.
Eating disorders include a group of syndromes with a significant impact on young women, mostly in pubertal age. They result from the interaction of many factors, including social, cultural, personal and biological ones. Among biological factors, immunological alterations have been recently implicated in the etiology of other psychiatric disorders, so we decided to make a systematic review in order to establish whether the innate immune response, particularly proinflammatory cytokines, is associated with eating disorders pathogenesis. Moreover, we point out that a greater knowledge of their etiology would let us to combat these disorders by considering new therapeutic targets.
Grado en Medicina
Proinflammatory cytokines, Interleukin 1 beta, Interleuquina 6, Citoquinas proinflamatorias, Interleukin 6, Bulimia nerviosa, Anorexia nervosa, Trastornos de la conducta alimentaria, Interleuquina 1 beta, Factor de necrosis tumoral alfa, Tumour necrosis factor alpha, Anorexia nerviosa, Bulimia nervosa, Eating disorders
Proinflammatory cytokines, Interleukin 1 beta, Interleuquina 6, Citoquinas proinflamatorias, Interleukin 6, Bulimia nerviosa, Anorexia nervosa, Trastornos de la conducta alimentaria, Interleuquina 1 beta, Factor de necrosis tumoral alfa, Tumour necrosis factor alpha, Anorexia nerviosa, Bulimia nervosa, Eating disorders
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