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Recolector de Ciencia Abierta, RECOLECTA
Bachelor thesis . 2018
License: CC BY NC ND
image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
Recolector de Ciencia Abierta, RECOLECTA
Bachelor thesis . 2018
License: CC BY NC ND
image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
UCrea
Bachelor thesis . 2018
License: CC BY NC ND
Data sources: UCrea
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Resultados del tratamiento quirúrgico del tumor de Klatskin

Results of the surgical treatment of the Klatskin tumor
Authors: Díaz San Miguel, Patricia;

Resultados del tratamiento quirúrgico del tumor de Klatskin

Abstract

INTRODUCCIÓN: El colangiocarcinoma es el segundo tumor maligno hepático primario más frecuente de etiología desconocida originado en los conductos biliares. Es más frecuente en varones en edades comprendidas entre los 50 y 60 años. En este estudio se plantea la hipótesis y se intentará comprobar si una cirugía más radical se asocia a mayor borde libre y posiblemente, a mayor supervivencia. OBJETIVO: Conocer qué tipo de intervención quirúrgica logra mayor supervivencia y produce menos complicaciones. Por una parte, se compara una resección ampliada, la cual incluye una resección de la vía biliar asociada a una hepatectomía derecha o bien izquierda, y por otra, una resección limitada a la vía biliar. MÉTODOS: Revisión retrospectiva de historias clínicas de pacientes intervenidos de tumor de Klatskin en el Hospital Universitario Marqués de Valdecilla entre 1996 y 2017.RESULTADOS: Se estudiaron 26 pacientes (18 hombres; 8 mujeres) con una media de edad de 66,8 años. El 50% de los pacientes en el diagnóstico presentaban 3 o más factores de riesgo, el 53,8% eran tipo II en la clasificación de Bismuth, el 57,7% tuvieron una resección ampliada, el 50% borde libre de tumor y la complicación más frecuente fue la fístula (42,3%). El 57,7% de los pacientes presentaron recidiva. La media de supervivencia fue de 85 meses. CONCLUSIONES: La resección ampliada, con hepatectomía parcial se asocia significativamente a una mayor frecuencia de borde de resección libre. Sin embargo, los casos con borde libre no presentaron una supervivencia a largo plazo significativamente mayor. No se obtuvieron diferencias estadísticamente significativas al comparar las complicaciones postoperatorias con el tipo de resección del tumor.

INTRODUCTION: Cholangiocarcinoma is the second most frequent primary hepatic malignant tumor of unknown etiology that originates in the bile ducts. It is more common in men between the ages of 50 and 60 years. In this study, the hypothesis is proposed and an attempt will be made to verify if a more radical surgery is associated with a greater free margin and possibly with a longer survival. OBJECTIVE: To know what type of surgical intervention achieved a greater survival and produce fewer complications. On the one hand, an extended resection is compared, which includes a resection of the bile duct associated with a right or left hepatectomy, and on the other hand, a resection limited to the bile duct. METHODS: Retrospective review of the clinical records of patients operated on by Klatskin tumor at the Marqués de Valdecilla University Hospital between 1996 and 2017.RESULTS: Twenty-six patients were studied (18 men, 8 women) with an average age of 66.8 years. 50% of the patients in the diagnosis had 3 or more risk factors, 53.8% were type II in the Bismuth classification, 57.7% had a total resection, 50% had a tumor-free border and the complication most common was fistula (42.3%). 57.7% of patients presented recurrence. The average survival was 85 months. CONCLUSIONS: Extended resection with partial hepatectomy is significantly associated with a higher frequency of free resection edge. However, cases with free margin do not have a significantly longer long-term survival. No statistically significant differences were found with postoperative complications with the type of tumor resection.

Grado en Medicina

Country
Spain
Related Organizations
Keywords

Klatskin, Intervención quirúrgica, Supervivencia, Complications, Survival, Surgical intervention, Complicaciones

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popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
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This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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