
The RelA (p65) subunit of transcription factor NF-kappaB plays a critical role in development, and rela(-/-) knockout mice die in utero from massive liver apoptosis. Only partial sequences of the mouse Rela gene are available. We have determined the genomic structure of mouse Rela and promoter, and have mapped the gene to chromosome 19B1-3.
Base Sequence, Chromosomes, Human, Pair 11, Molecular Sequence Data, NF-kappa B, Transcription Factor RelA, Exons, Physical Chromosome Mapping, Introns, Chromosome Banding, Mice, Animals, Humans, Cloning, Molecular, Promoter Regions, Genetic, In Situ Hybridization, Fluorescence
Base Sequence, Chromosomes, Human, Pair 11, Molecular Sequence Data, NF-kappa B, Transcription Factor RelA, Exons, Physical Chromosome Mapping, Introns, Chromosome Banding, Mice, Animals, Humans, Cloning, Molecular, Promoter Regions, Genetic, In Situ Hybridization, Fluorescence
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