The treatment of patients with adenocarcinoma of the lung depends on the clinical stage of the disease: surgical therapy in stage I or II, multimodal therapy including surgery in stage IIIA, multimodal therapy including combination of cytotoxic drugs and radiation in inoperable cases. Future therapeutic strategies for lung cancer should include the use of spiral CT, which can detect lung tumors with < 2 cm in diameter, in group health screening for the early diagnosis of adenocarcinoma, and the use of recently new developed anticancer for the treatment of inoperable cases of adenocarcinoma. Compared to the classical combined chemotherapy, future therapeutic modalities should be more effective for improving prognosis and quality of life of lung cancer patients.