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Histopathological diagnostic approach in Saguinus leucopus with cronic chagasic cardiomyopathy in rehabilitation and re-introduction programs

Authors: Acero Mondragón, Edward Javier; Maldonado Arango, María Inés; Angulo Calderón, Nohora Mercedes;

Histopathological diagnostic approach in Saguinus leucopus with cronic chagasic cardiomyopathy in rehabilitation and re-introduction programs

Abstract

Saguinus leucopus es un primate endémico de Colombia considerado vulnerable, además, con la distribución geográfica más restringida entre Saguinus sp. Así mismo, es reconocido como reservorio natural de Trypanosoma cruzi, por compartir la distribución geográfica con vectores, como Rhodnious prolixus y Triatoma dimidiata ; sin embargo, el primate no presenta cardiomiopatía chagásica crónica de manera natural. Aproximaciones histopatológicas para diagnosticar cardiomiopatía chagásica crónica en S. leucopus, se deben establecer cuando en programas de rehabilitación y de reintroducción se hallen en los cuadros hemáticos Trypanosomas spp., paralelamente con decesos en las mismas colonias y que en las necropsias se demuestre cardiomegalias y esplenomegalias. Allí, la histopatología en corazón puede demostrar miocarditis, circunscrita al miocardio con infiltrado linfomonocitario inmunifenotipificado CD 19 negativo, pero CD3 y CD68 positivo, hallazgos que, junto a los cardiomiocitos conteniendo formas bastoniformes de 2 micras de diámetro, encerradas en una "vaina" eosinófila de grosor homogéneo, son característicos de "pseudoquistes" amastigóticos miocárdicos de cardiomiopatia chagásica, propios de los causados por la especie T. cruzi .

5 páginas

Country
Colombia
Related Organizations
Keywords

Cardiomiopatia chagásica, S. leucopus, T. cruzi

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
Green