Postantifungal effect of anidulafungin against Candida albicans, Candida dubliniensis, Candida africana, Candida parapsilosis, Candida metapsilosis and Candida orthopsilosis
Postantifungal effect of anidulafungin against Candida albicans, Candida dubliniensis, Candida africana, Candida parapsilosis, Candida metapsilosis and Candida orthopsilosis
El estudio evaluó el efecto postantifúngico (PAFE) de anidulafungina contra Candida albicans, Candida parapsilosis, C. dubliniensis, C. africana, C. metapsilosis y C. orthopsilosis. Se analizaron 21 cepas mediante estudios de PAFE y curvas de letalidad (time-kill). Los resultados mostraron que anidulafungina produjo un efecto postantifúngico prolongado frente a la mayoría de las cepas estudiadas y alcanzó actividad fungicida en algunos aislamientos. El trabajo concluye que anidulafungina presenta un PAFE significativo y prolongado contra especies relacionadas con C. albicans y C. parapsilosis.
This work was supported by Consejería de Educación, Universidades e Investigación of Gobierno Vasco-Eusko Jaurlaritza [GIC15/78 IT990-16] and Universidad del País Vasco/Euskal Herriko Unibertsitatea (UPV/EHU) [UFI 11/25 and ESPDOC17/109 to S. G.-A.].
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