
handle: 10810/24707
La tesis se enmarca dentro de la química de los 1H-1,2,3-triazoles y sus sales de N-alquil-triazolio. El trabajo realizado contempla los siguientes objetivos:1.- Sintetizar y estudiar los 1H-1,2,3-triazoles como plantillas moleculares de fármacos reguladores de [Ca2+] intraplasmático en músculo esquelético2.- Transformar triazoles 1,4-disustituidos en 1,5-disustituidos via N-desalquilación regiocontrolada de sales de triazolio3.- Desarrollar nuevos 1,2,3-triazoles como agentes directores en reacciones de funcionalizaciónC¿H.
356 p.
compuestos heterocíclicos, coordination compounds, heterocyclic compounds, compuestos de coordinación
compuestos heterocíclicos, coordination compounds, heterocyclic compounds, compuestos de coordinación
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