Among 162 human isolates of Trichosporon the author isolated according to "crucial" signs (Guého et al. 1992, 1994) the following as dominant: T. mucoides (41%) and T. asahii (33%), T. inkin, T. ovoides and others as well as non-pathogenic T. pullulans were rare in their investigation. To the originally most frequently reported type T. cutaneum belonged less than 10% of the total number of isolates. The variability of physiological and biological signs did not make classification of 5% isolated Trichosporon strains possible. The disc diffusion method confirmed resistance of the tested strains to 5-fluorocytosine, and inhibition by polyene and azole antimycotics.