To differentiate or not to differentiate?

Developmental regulation of the cell cycle is an important determinant of tissue size and shape. Equally important is regulated withdrawal from the cell cycle to allow cells to differentiate. Recent evidence supports a direct link between transcriptional regulation of the cell cycle machinery and cell differentiation.

Related Organizations

UNC Lineberger Comprehensive Cancer Center
United States

Keywords

Transcription, Genetic, Cell Cycle, Nuclear Proteins, Cell Differentiation, Nerve Tissue Proteins, Juvenile Hormones, Animals, Drosophila Proteins, Drosophila, Cells, Cultured, Transcription Factors

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