Phototransduction and calcium.
Copyright policy )Phototransduction and calcium.
In the early 1970s it became clear that an unknown intracellular messenger participated in signal transduction in retinal rod cells. Ca2+ and cGMP had been considered as candidates for such a messenger until 1985 when the cGMP-gated conductance of the plasma membrane was discovered. However, for the last several years, Ca2+ has taken revenge as a signal molecule which contributed to the processes underlying the photoreceptor cell recovery. This review describes the overall picture of phototransduction molecular mechanisms with special emphasis on participation of Ca2+ in visual cell signalling.
- Lomonosov Moscow State University Russian Federation
Lipoproteins, Calcium-Binding Proteins, Nerve Tissue Proteins, Models, Biological, Ion Channels, Retina, Hippocalcin, Recoverin, Animals, Humans, Calcium, Eye Proteins, Cyclic GMP, Ocular Physiological Phenomena, Vision, Ocular
Lipoproteins, Calcium-Binding Proteins, Nerve Tissue Proteins, Models, Biological, Ion Channels, Retina, Hippocalcin, Recoverin, Animals, Humans, Calcium, Eye Proteins, Cyclic GMP, Ocular Physiological Phenomena, Vision, Ocular
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