Time elapsed between absorption of toxic mushrooms and occurrence of first disorders (mainly digestive), lead to distinguish 2 kinds of syndromes. Early syndromes, beginning before the 6th hour, follow a generally favourable course. Incriminated toxins induce digestive, neurosensory or neurovegetative disorders, sometimes severe but reversible. Late syndromes, beginning after the 6th hour, endanger patient's life. Incriminated toxins can lead to irreversible liver and kidneys damage. Medical treatment aims at eliminating toxins and inhibiting cellular penetration of cytolytic toxins. Symptomatic intensive care, directed by clinical and biological indications, ensure correction of plasmatic disorders and compensation for hepatic and renal severe failure.