
handle: 10722/176571
The invention consists of episomal expression cassettes for expression of a tran sgene in gene therapy. The expression cassettes consist of regulatory elements of the human cytokeratin gene and a transgene. The invention also includes liposomes for tran sfection of epithelial tissue with the cassettes in treatment of cystic fibrosis, emphyserma , cancers of epithelial origin arising in the lung or other organs.
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