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Sobrevida global, sobrevida libre de enfermedad y respuesta global de los pacientes mayores de 14 años con leucemia linfoide aguda, experiencia en el Hospital Militar Central durante el periodo 2006 a 2012.

Authors: Castillo Peñuela, Erwing; Pierre, Marc Edy; Castellanos Mejia, Ana M.;

Sobrevida global, sobrevida libre de enfermedad y respuesta global de los pacientes mayores de 14 años con leucemia linfoide aguda, experiencia en el Hospital Militar Central durante el periodo 2006 a 2012.

Abstract

Introducción: La leucemia linfoblástica aguda (LLA) de los adultos a pesar de tener una tasa de remisión completa (RC) entre el 75 al 95%, solo logra una sobrevida libre de enfermedad (SLE) a largo plazo del 30 al 40%. En Colombia el único estudio publicado en el 2007 usando el protocolo de quimioterapia HyperCVAD documento una tasa de RC de 61% y una SLE a 3 años del 0%. Objetivos. Determinar la tasa de respuesta completo al manejo quimioterapéutico de la LLA, así como la tasas de SLE y sobrevida global (SG) a 1 y 3 años de los pacientes mayores de 14 años tratados con diferentes esquemas de quimioterapia en el Hospital Militar Central (HMC) entre los años 2006 a 2012.

Introduction: Although acute lymphoblastic leukemia (ALL) in adult population have complete remission (CR) rates ranging between 75 and 95%, only 30-40% of patients achieved disease free survival (DFS) in the long term. In Colombia the only study published in 2007 using the chemotherapy protocol HyperCVAD found CR rate of 61% and a 3-year DFS of 0%. Objectives: to determine the CR rate to chemotherapeutic management of ALL, as well as the rates of DFS and overall survival (OS) at 1 and 3 years for patients older than 14 years treated with different chemotherapy regimens in Hospital Militar Central during the years 2006-2012.

Country
Colombia
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Keywords

DFCI, Adult, Leukemia, HyperCVAD, LEUCEMIA, GMALL, Colombia, Acute, Aguda, Lymphoblastic, Fralle 93, ENFERMEDADES HEMATOLOGICAS, Chemotherapy, ONCOLOGIA, Leucemia, Linfoblastica, Quimioterapia, Adultos

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
Green
Related to Research communities
Cancer Research