
handle: 10654/10728
Introducción: La leucemia linfoblástica aguda (LLA) de los adultos a pesar de tener una tasa de remisión completa (RC) entre el 75 al 95%, solo logra una sobrevida libre de enfermedad (SLE) a largo plazo del 30 al 40%. En Colombia el único estudio publicado en el 2007 usando el protocolo de quimioterapia HyperCVAD documento una tasa de RC de 61% y una SLE a 3 años del 0%. Objetivos. Determinar la tasa de respuesta completo al manejo quimioterapéutico de la LLA, así como la tasas de SLE y sobrevida global (SG) a 1 y 3 años de los pacientes mayores de 14 años tratados con diferentes esquemas de quimioterapia en el Hospital Militar Central (HMC) entre los años 2006 a 2012.
Introduction: Although acute lymphoblastic leukemia (ALL) in adult population have complete remission (CR) rates ranging between 75 and 95%, only 30-40% of patients achieved disease free survival (DFS) in the long term. In Colombia the only study published in 2007 using the chemotherapy protocol HyperCVAD found CR rate of 61% and a 3-year DFS of 0%. Objectives: to determine the CR rate to chemotherapeutic management of ALL, as well as the rates of DFS and overall survival (OS) at 1 and 3 years for patients older than 14 years treated with different chemotherapy regimens in Hospital Militar Central during the years 2006-2012.
DFCI, Adult, Leukemia, HyperCVAD, LEUCEMIA, GMALL, Colombia, Acute, Aguda, Lymphoblastic, Fralle 93, ENFERMEDADES HEMATOLOGICAS, Chemotherapy, ONCOLOGIA, Leucemia, Linfoblastica, Quimioterapia, Adultos
DFCI, Adult, Leukemia, HyperCVAD, LEUCEMIA, GMALL, Colombia, Acute, Aguda, Lymphoblastic, Fralle 93, ENFERMEDADES HEMATOLOGICAS, Chemotherapy, ONCOLOGIA, Leucemia, Linfoblastica, Quimioterapia, Adultos
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