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Búsqueda de marcadores de traumatismo craneal en boxeo.

Authors: Gutiérrez García, Pablo;

Búsqueda de marcadores de traumatismo craneal en boxeo.

Abstract

Los traumatismos craneoencefálicos (TCE) son accidentes que pueden causar lesiones encefálicas de diferente magnitud con consecuencias relevantes para el paciente y el sistema sanitario. En algunos deportes son relativamente frecuentes, debido a la naturaleza del deporte, siendo conocidas como conmociones relacionadas con el deporte (SRC). Los marcadores bioquímicos validados son poco asequibles y poco sensibles. En este contexto, los microRNA (miRNA), un tipo de ARN de cadena sencilla, los cuales pueden encontrarse circulantes en varios fluidos corporales como la sangre, han emergido como nuevos biomarcadores en diferentes situaciones fisiológicas y patológicas. En este estudio hemos analizado los niveles plasmáticos de un panel de nueve miRNA previamente descritos como alterados en pacientes con TCE, para evaluar su utilidad como nuevos biomarcadores de SRC agudo en boxeadores varones pertenecientes al equipo olímpico español. Nuestros resultados sugieren que el miR-206 es un buen candidato como nuevo biomarcador de SRC al disminuir significativamente sus niveles plasmáticos tras un combate y relacionarse estrechamente su cambio con otros biomarcadores clásicos

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    influence
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
Green