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Inmunidad innata, silenciamiento génico y defensa antiviral

Authors: Llave Correas, César;

Inmunidad innata, silenciamiento génico y defensa antiviral

Abstract

En esta charla se presentarán los resultados más recientes del grupo en relación a efecto de silenciamiento génico sobre el desarrollo de las infecciones vitales en plantas. El silenciamiento génico es un mecanismo regulador de la expresión génica que actúa sobre los genomas del virus y de la planta. Más allá de su aparente función como mecanismo antiviral, el silenciamiento controla la expresión de genes que definen el signo de las interacción planta-virus. Recientemente hemos aplicado diversas estratégias transcriptómicas que nos permiten selectivamente identificar genes asociados al proceso viral cuya regulación es dependiente de silenciamiento génico. Algunos de estos genes constituyen componentes esenciales en las vías de señalización de la inmunidad innata de las plantas. Los resultados que se presentan ponen de manifiesto la interacción entre estas vías de señalización y la infección vira Nuestros datos sugieren que el efecto antiviral de la maquinaria de silenciamiento radica en gran medida en el control de elementos conservados de la inmunidad de la planta y no tanto en el autosilenciamiento de los genomas virales. En esta charla se presentan además datos relativos a las alteraciones metabólicas asociadas a la infección viral. Este es un aspecto esencial para entender la activación de respuestas de susceptibilidad y/o defensa.

Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech.

Country
Spain
Related Organizations
Keywords

Inactivación génica, Silenciamiento génico, Defensa antiviral

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
Green