Powered by OpenAIRE graph
Found an issue? Give us feedback
addClaim

Unión bilirrubina-albúmina en recién nacidos a término sometidos a nutrición parenteral total

Authors: Domínguez Ortega, F.; González Azpeitia, G.; Domenech Martínez, E.;

Unión bilirrubina-albúmina en recién nacidos a término sometidos a nutrición parenteral total

Abstract

Evaluamos la influencia de los niveles de Iípidos plasmáticos aportados en la nutrición parenteral sobre la unión bilirrubina-albúmina de 12 recién nacidos a término portadores de patologías severas. Como controles se seleccionaron 2 grupos de igual número de neonatos, pero que estaban alimentados con lactancia materna o artificial. La capacidad de reserva de unión de la albúmina descendió en los recién nacidos sometidos a nutrición parenteral (52,3 frente a 72,9/73,5). Esta disminución se correlacionó con mayores concentraciones de ácidos grasos libres (r = 0,9234, p < 0, 001 ), colesterol (r =0,9049, p < 0,001) y triglicéridos (r = 0,8802, p < 0,001). La clara influencia de los parámetros lipídicos estudiados sobre la unión bilirrubina-albúmina nos invita apensar en el uso sistemático de heparina para movilizar la lipoproteín-lipasa del endotelio vascular y promover un mejor manejo de los lípidos en los neonatos a término, sobre todo si existe hiperbilirrubinemia importante.

We evaluate the influence of plasma lipid levels supplied in parenteral nutrition, on the bilirubin-albumin binding of 12 term newborns with severe pathologies. As controls we selected 2 groups of an equal number o newborns who were receiving maternal or artificial lactation. The reserved albumin binding capacity decreased in newborns subjected to parenteral nutrition (52.3 versus 72.9/73.5). This decrease correlated positively with greater concentrations of free fatty acids (r = 0.9234, p < 0.001), cholesterol (r = 0.9049, p < 0.001), and triglycerides (r = 0.8802, p < 0.001). The clear influence of the studied lipid parameters on the bilirubin albumin binding, invites us to consider the systematic use of heparin for the mobilization of lipoprotein-lipase from the vascular endothelium and to promote a better management of lipids in term newborns, especially if there is an important hyperbilirubinemia.

SCIE

205

201

5

Keywords

Bilirrubina, Recién nacido, Lípidos, Bilirubin, Nutrición parenteral, 320110 Pediatría, Newborn, Parenteral nutrition, 32 Ciencias médicas, Lipids

  • BIP!
    Impact byBIP!
    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    0
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Average
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Average
Powered by OpenAIRE graph
Found an issue? Give us feedback
selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
Upload OA version
Are you the author of this publication? Upload your Open Access version to Zenodo!
It’s fast and easy, just two clicks!