Powered by OpenAIRE graph
Found an issue? Give us feedback
image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Recolector de Cienci...arrow_drop_down
image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
versions View all 1 versions
addClaim

Transmisión congénita de la Tripanosomiasis Americana en Santa Cruz de la Sierra, Bolivia

Authors: Guillen Zabala, Helmuth;

Transmisión congénita de la Tripanosomiasis Americana en Santa Cruz de la Sierra, Bolivia

Abstract

La enfermedad de Chagas o tripanosomiasis americana es una antropozoonosis endémica de América Latina, que se extiende desde el sur de EE.UU. y México, en su límite norte, hasta Argentina y Chile por el sur. Las políticas de control realizadas en áreas endémicas han llevado a reducir considerablemente la transmisión vectorial, que se ha traducido en un notable cambio en su epidemiología. La enfermedad de Chagas en Bolivia tiene los indicadores epidemiológicos básicos más elevados de América. La infección congénita es actualmente una de las más importantes vías de transmisión del T. cruzi y una de las responsables de la urbanización de la enfermedad y de su aparición en áreas alejadas de las zonas endémicas. El presente trabajo contribuye a mejorar los conocimientos sobre la transmisión congénita de la infección en una zona con alta prevalencia de la enfermedad, y de esta forma poder desarrollar medidas que ayuden a disminuir la continua propagación de esta enfermedad. En este sentido, se realizó un estudio de la prevalencia de la enfermedad de Chagas en mujeres embarazadas que acuden al Hospital Municipal de la Mujer “Dr. Percy Boland Rodriguez” para ser atendidas, encontrándose una prevalencia de periodo para las mujeres embarazadas de 19,5%, y una transmisión congénita en el 1,4%. Se realizó un análisis del perfil sociodemográfico de las mujeres embarazadas, donde se observó en las madres con infección Chagásica una mayor edad, procedencia periurbana y una mayor proporción de migración de otros departamentos endémicos para la enfermedad, además de un menor nivel educativo. En el análisis del perfil clínico de las mujeres embarazadas, se observó un mayor número de antecedentes clínicos personales, multiparidad y partos vaginales previos en las madres infectadas, encontrándose en las características de la gestación actual más embarazos de término, mayor frecuencia de anemia y de RPM en las madres con infección. En el perfil clínico de la infección congénita se observó que las madres que transmiten la infección a sus hijos presentan mayor edad y multiparidad, además de mayor frecuencia de partos pretérminos y RPM. Se observó también mayor frecuencia de sexo femenino e ingresos en la unidad de Neonatología en los recién nacidos infectados. Se identifican como factores de riesgo asociados a la infección materna la edad mayor a 20 años, la presencia de antecedentes personales y la edad gestacional de término. Los factores de riesgo asociados a la infección congénita fueron la edad materna, la RPM, el desarrollo de sepsis neonatal y la necesidad de ingreso en una unidad de Neonatología.

Chagas disease or American trypanosomiasis is an endemic anthropozoonosis of Latin America, which extends from the southern USA and Mexico, at its northern boundary, to Argentina and Chile to the south. Control policies carried out in endemic areas have led to a significant reduction in vector transmission, which has resulted in a notable change in epidemiology. Chagas disease in Bolivia has the highest basic epidemiological indicators in the Americas. Congenital infection is currently one of the most important transmission routes of T. cruzi and one of those responsible for the urbanization of the disease and its occurrence in areas far from the endemic areas. The present work contributes to improve knowledge about the congenital transmission of infection in an area with a high prevalence of the disease, and in this way to develop measures that help to reduce the continuous spread of this disease. In this sense, a study of the prevalence of Chagas disease in pregnant women that go to the Hospital Municipal de la Mujer “Dr. Percy Boland Rodriguez” to be attended, with a prevalence of period for pregnant women of 19.5%, and congenital transmission in 1.4%. An analysis of the sociodemographic profile of pregnant women was carried out, where a higher age, periurban origin and a higher proportion of migration from other departments endemic to the disease were observed in the mothers with Chagas disease, in addition to a lower level of education. In the analysis of the clinical profile of pregnant women, a greater number of personal clinical antecedents, multiparity and previous vaginal deliveries were observed in the infected mothers, being found in the characteristics of the current gestation more term pregnancies, greater frequency of anemia and of RPM in mothers with infection. In the clinical profile of the congenital infection, it was observed that the mothers who transmit the infection to their children present a greater age and multiparity, besides a higher frequency of preterm deliveries and RPM. There was also a higher frequency of female sex and income in the neonatal unit in infected newborns. The risk factors associated with maternal infection are identified as being older than 20 years, the presence of a personal history and the gestational age at term. Risk factors associated with congenital infection were maternal age, RPM, the development of neonatal sepsis, and the need for admission to a Neonatal unit.

Keywords

tripanosomiasis americana, Chagas congénito, enfermedad de Chagas, UNESCO::CIENCIAS MÉDICAS, :CIENCIAS MÉDICAS [UNESCO]

  • BIP!
    Impact byBIP!
    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    0
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Average
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Average
Powered by OpenAIRE graph
Found an issue? Give us feedback
selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
Green