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Transformación de leucoplasia verrugosa proliferativa en carcinoma oral: diez años de seguimiento

Authors: Navarro, Cláudia Maria; Sposto, Maria Regina; Sgavioli Massucato, Elaine Maria; Aparecida Onofre, Mirian;

Transformación de leucoplasia verrugosa proliferativa en carcinoma oral: diez años de seguimiento

Abstract

Los autores presentan un caso de leucoplasia verrugosa proliferativa (LVP) en varón de 78 años de edad. Fue inicialmente presentado como un caso de leucoplasia en lengua pero un estudio microscópico en 1991 reveló la presencia de displasia epitelial leve. Tras 5 años de seguimiento, la lesión sufrió cambios de tamaño y localización y tuvo comportamiento recidivante. En 1996, un área eritematosa granular e indurada que apareció en lengua resultó ser un carcinoma de células escamosas microinvasivo cuando se estudió microscópicamente. Tras una revisión del comportamiento clinicopatológico de esta entidad, los autores concluyeron que se trataba de una leucoplasia verrugosa proliferativa, cuyo diagnóstico es difícil y retrospectivo, como indicaban otros autores. Los autores enfatizan la importancia del examen periódico detallado clínico e histológico de este tipo de lesiones con el fin de detectar signos de malignidad precozmente.

The authors present a case of proliferative verrucous leukoplakia (PVL) in a 78-year-old man. It was initially presented as leukoplakia on the tongue but a microscopic investigation in 1991 revealed it to be a mild epithelial dysplasia. After 5 years of follow-up, the lesion presented changes in size and location, and a recidivant behavior. In 1996, a red granular and indurated area that appeared on the tongue was found to be a microinvasive squamous cell carcinoma when microscopically investigated. After a review of the clinicopathologic behavior of this entity, the authors concluded that it was a typical PVL, whose diagnosis is difficult and retrospective, as indicated by others. The authors emphasize the importance of periodic detailed clinical and histological examination of this type of lesions in order to detect early signs of malignancy.

Country
Brazil
Keywords

Oral, squamous cell carcinoma, Male, Dysplasia, malignant transformation, Time Factors, review, 610, Odontología, Cell Transformation, papilomatosis, epithelial hyperplasia, histology, carcinoma de células escamosas, clinical examination, dysplasia, male, Epithelial hyperplasia, Squamous cell carcinoma, case report, follow up, Humans, human, displasia, Papillomatosis, Aged, Neoplastic, Leucoplasia verrugosa proliferativa, Carcinoma, :CIENCIAS MÉDICAS [UNESCO], papilloma-tosis, Ciencias de la salud, proliferative verrucous leukoplakia, aged, Cell Transformation, Neoplastic, Squamous Cell, epithelium hyperplasia, leukoplakia, papillomatosis, mouth carcinoma, UNESCO::CIENCIAS MÉDICAS, Carcinoma, Squamous Cell, Proliferative verrucous leukoplakia, hiperplasia epitelial, Mouth Neoplasms, Leukoplakia, Oral, Follow-Up Studies

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
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Green