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Actualización en liquen plano oral

Authors: Villegas Acosta, Flor Ángela; Ruiz R., Sandra María; Velásquez Osorno, José Manuel; Flórez M., Gloria Amparo; Londoño L., Martha Luz;

Actualización en liquen plano oral

Abstract

RESUMEN: El liquen plano (LP) es un desorden inflamatorio del epitelio escamoso estratificado relativamente común. Las lesiones pueden afectar la piel y membranas mucosas. El Liquen Plano Oral (LPO), usualmente, presenta una morfología y distribución característica,pudiendo mostrar una disposición confusa de patrones y lormas de tal manera que otros desórdenes pueden simularlo clínicamente. El LP es probablemente de origen multitectorial. algunas veces es inducido por drogas o máteriales dentales, a menudo idiopático y con una inmunopatogénesis que involucra a las células Ten particular. La etiopetogénesis parece ser compleja con interacciones entre lactores gen éticos, ambientales y de estilo de vida, aunque en la actualidad se han aclarado varios aspectos acerca de los mecanismos involucrados y han surgido nuevas asociaciones interesantes con otras enfermedades. El manejo del LP aún no es satisfactorio, pues hasta ahora no existe un tratamiento definitivo y aunque no hay método curativo disponible, la inmunomodulación puede controlar la condición. Clásicamente se ha considerado como una entidad premaligna, pero estudios recientes sugieren que existe una condición conocida como displasia liquenoide que requiere diagnóstico diferencial con el LP Se precisa más investigación en los aspectos gen éticos, ambientales, potencial maligno, asociación con otros desórdenes y más estudios clínicos acerca de su terapia.

ABSTRACT: Licben planus (LP) is a relatively common disorder of the stratilied squamous epithelia. Lesions may affect other mucosae and/or skin. Orallichen planus (OLP) usually has a characteristic morphology and distribution, but OLP may also present a conlusing array of pattern and forms and other disorders may clinically simulate OLP Lichen planus is probably of multifactorial origin, sometimes induced for drugs or dental materials, often idiopathic, and with an immunopathogenesis involving T cells in particular. The etiopathogenesis appears to be complex, with interactions between and among genetic, environmental, and lilestyle Iectors, but much has now been cleritied about the mechanisms in volved, and interesting new associations with other diseeses, have emerged. The management 01 LP is stiJl not satisfactory, and there is as yet no definitive treatment, but there have been advances in the control 01 the condition. There is not curative treatment available, immunomodulation, however, can control the condition. Classical/y, it has been considered as premalignant entity, but recent researches suggest that there is a condition known as lichenoid dysplasia that requires ditterenciel diagnostic with LP ft is necessary more research into the genetic and environmental espects, its malignant potential, associations with other disorders and more clinical studies about therapy.

Country
Colombia
Keywords

Enfermedades de la boca, Stomatitis, 617, Mouth - diseases, 610, Apoptosis, Estomatitis

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
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