
handle: 10495/32683
RESUMEN: Introducción: los vinagres de bambú se utilizan en los países orientales en aplicaciones farmacéuticas, con la especie Guadua angustifolia Kunth no se han encontrado investigaciones similares. Evaluar la actividad antiséptica del vinagre de guadua permitiría avanzar en estos desarrollos. Objetivo: determinar la sensibilidad de las bacterias Pseudomona aeruginosa y Staphylococcus aureus frente al vinagre de guadua, los cambios con la concentración y el pH. Métodos: la actividad antimicrobiana se midió por difusión en agar en medio Muller Hinton. Se ensayaron vinagres a concentraciones entre 100, 80, 60, 40 y 20 % a pH entre 3 y 6. Se estableció la concentración mínima inhibitoria. Resultados: el vinagre de guadua presenta actividad antiséptica a concentraciones superiores a 12 mg/mL en base seca, rango de pH 2 a 6, reduce en 4 log la concentración de microorganismos y muestra mayor actividad antiséptica contra S. aureus. Conclusiones: la actividad antiséptica del vinagre de bambú comparado con el de otra especie, obtenido en condiciones similares a las que se realizaron en este estudio, se obtiene una mayor actividad para el vinagre de G. angustifolia, lo cual permite demostrar el gran potencial de este para el desarrollo de formulaciones con actividad antiséptica.
ABSTRACT: Introduction: bamboo vinegars are used in the Asian countries for pharmaceutical applications, but the Guadua angustifolia Kunth species has not been similarly researched in this field. The assessment of the antiseptic activity of guadua vinegar would allow moving forward in this direction. Objective: to determine the antiseptic action of guadua vinegar against Pseudomona aeruginosa and Staphylococcus aureus bacteria, with several changes in concentration and the pH. Methods: the antimicrobial activity was measured through the agar diffusion in Muller Hinton medium. Guadua vinegars were tested at 100, 80, 60, 40, and 20 % concentrations and the pH ranged 3 to 6. The minimum inhibitory concentration was set. Results: guadua vinegar showed antiseptic properties at concentrations over 12 mg/mL, on dry weight and pH range of 2 to 6; it reduced by 4 log the final microorganism concentration and exhibited greater antibacterial activity against S. aureus. Conclusions: comparing the antiseptic activity of bamboo vinegar with that of another species, under conditions similar to those in this study, results in greater activity for Guadua angustifolia vinegar, which can prove its great potential for the development of antiseptic formulations
COL0065152
580, Staphylococcus aureus, Antiseptics, 330, http://aims.fao.org/aos/agrovoc/c_3407, Ácido Acético, http://aims.fao.org/aos/agrovoc/c_26646, Vinegar, Antisépticos, Pseudomonas aeruginosa, Vinagre, Guadua angustifolia, Acetic Acid
580, Staphylococcus aureus, Antiseptics, 330, http://aims.fao.org/aos/agrovoc/c_3407, Ácido Acético, http://aims.fao.org/aos/agrovoc/c_26646, Vinegar, Antisépticos, Pseudomonas aeruginosa, Vinagre, Guadua angustifolia, Acetic Acid
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