
handle: 10481/36374
La enfermedad cardiovascular, y su frecuente resultado final, el fallo cardíaco del ventrículo izquierdo, son la principal causa de morbimortalidad en los países desarrollados. La investigación con células madre podría regenerar una variedad de células que incluye a los cardiomiocitos. Se han utilizado diferentes fuentes celulares para la terapia regenerativa cardíaca, incluyendo células madre cardíacas, mioblastos de músculo esquelético, células madre derivadas de la médula ósea, células madre mesenquimales, células madre embrionarias y células madre pluripotenciales inducidas. En la presente revisión se recogen las diferentes fuentes celulares utilizadas y el ámbito donde han sido usadas: ensayos clínico o estudios experimentales.
Cardiovascular disease and its frequent consequence, left ventricular failure, are the leading cause of morbidity and mortality in the developed countries. The stem cell research could be useful regenerating a variety of tissue cells, including cardiomyocytes. Different sources of stem cells for regenerative cardiac therapy have been reported, including cardiac stem cells, skeletal myoblasts, bone marrow-derived stem cells, mesenchymal stem cells, embryonic stem cells and induced pluripotent stem cells. The present review shows the different cell sources used as well as their field of application: clinical trials or experimental studies.
Stem cell therapy, Terapia con células madre, Enfermedad cardiaca, Cardiac regeneration, Heart disease, Regeneración cardiaca
Stem cell therapy, Terapia con células madre, Enfermedad cardiaca, Cardiac regeneration, Heart disease, Regeneración cardiaca
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