
handle: 10481/29584
La presente invención se refiere a nanopartículas poliméricas con un tamaño medio inferior a 200 nm, que comprende uno o más polímeros biodegradables, uno o más principios activos y al menos un tensoactivo, donde al menos un polímero biodegradable es poli(ε-caprolactona) y donde al menos un principio activo es doxorrubicina, y al uso de dichas nanopartículas para la preparación de medicamentos para el tratamiento de cáncer, preferiblemente cáncer de mama.
The invention relates to polymer nanoparticles having an average size of less than 200 nm, comprising one or more biodegradable polymers, one or more active principles and at least one surfactant, in which at least one biodegradable polymer is poly(ε-caprolactone) and at least one active principle is doxorubicin. The invention also relates to the use of said nanoparticles for the preparation of drugs for the treatment of cancer, preferably breast cancer.
Número de publicación: ES2386712 B1. Número de solicitud: 201130122.
Servicio Andaluz de Salud
Universidad de Granada
Nano-biotecnología, Preparaciones medicinales, Compuestos macromoleculares, A61P 35/00, Nanocapsulas, A61K 9/51, B82Y 5/00, A61K 47/34, A61K 31/704
Nano-biotecnología, Preparaciones medicinales, Compuestos macromoleculares, A61P 35/00, Nanocapsulas, A61K 9/51, B82Y 5/00, A61K 47/34, A61K 31/704
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