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image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Universidade de Lisb...arrow_drop_down
image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao
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Impacto da idade materna avançada nos desfechos obstétricos e perinatais

Authors: Costa, Ana Raquel Ferreira da;

Impacto da idade materna avançada nos desfechos obstétricos e perinatais

Abstract

A gestação em idade materna avançada (IMA) é, a nível mundial, uma realidade cada vez mais frequente na prática obstétrica. Contudo, não existe consenso na literatura quanto às suas potenciais implicações, quer para a mãe, quer para o feto e recém-nascido. Este estudo tem por objetivo comparar os desfechos obstétricos e perinatais em grávidas abaixo e acima dos 35 anos de idade, nos últimos 4 anos, no Centro Hospitalar Universitário Lisboa Norte/Hospital de Santa Maria (CHULN/HSM). Tratou-se de um estudo observacional retrospectivo, baseado na consulta de registos clínicos do programa ObsCare que incluiu 5000 gestações, as quais foram divididas em três grupos de acordo com a idade materna no momento do parto: 18-34 anos, 35-39 anos e ≥40 anos. A análise estatística foi realizada no software IBM SPSS Statistics 29, utlizando o Teste do Qui-quadrado de Homogeneidade de Pearson e Regressão Logística Binária Multivariável. Foram considerados significativos, valores de p < 0.05. Os resultados obtidos, após controlo para possíveis fatores de confundimento, revelaram que existe uma associação significativa entre a IMA e a ocorrência de diabetes gestacional, de hipertensão gestacional, de cromossomopatia, de morte fetal, de cesariana e de malformações congénitas. Em conclusão, com vista a tentar controlar e minimizar os riscos maternos e perinatais acrescidos (diabetes gestacional, hipertensão gestacional, cromossomopatia, morte fetal, cesariana e malformações congénitas), é essencial que haja uma vigilância reforçada da gravidez em mulheres com IMA.

Pregnancy in advanced maternal age (AMA) is becoming increasingly common in obstetric practice worldwide. However, there is no consensus in the literature regarding its potential implications for both the mother and the fetus/newborn. This study aims to compare obstetric and perinatal outcomes between pregnant women below and above 35 years of age over the past 4 years at the Centro Hospitalar Universitário Lisboa Norte/Hospital de Santa Maria (CHULN/HSM). It was a retrospective observational study based on the review of clinical records from the ObsCare program, which included 5000 pregnancies. The pregnancies were divided into three groups based on maternal age at the time of delivery: 18-34 years, 35-39 years, and ≥40 years. Statistical analysis was performed using IBM SPSS Statistics 29, using Pearson's Chi-squared test for homogeneity and multivariable binary logistic regression. A significance level of p<0.05 was considered. The results, after controlling for possible confounding factors, revealed a significant association between AMA and the occurrence of gestational diabetes, gestational hypertension, chromosomal abnormalities, fetal death, cesarean delivery, and congenital malformations. In conclusion, in order to control and minimize the increased maternal and perinatal risks associated with AMA (gestational diabetes, gestational hypertension, chromosomal abnormalities, fetal death, cesarean delivery, and congenital malformations), enhanced surveillance of pregnancy is essential for women of advanced maternal age.

Trabalho Final do Curso de Mestrado Integrado em Medicina, Faculdade de Medicina, Universidade de Lisboa, 2023

Country
Portugal
Related Organizations
Keywords

Desfechos perinatais, Domínio/Área Científica::Ciências Médicas, Desfechos obstétricos, Obstetrícia, Idade materna avançada

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
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