Fournier’s disease in an acute pathologic process of cellulitis and necrotising fascitis involving the male genitals with a mortalità of 30-50 %. The main causes are periurethral and perirectal infections, immunodepressive syndromes, diabetes mellitus and traumas. Mixed types of infections involve aerobic and anaerobic germs, the latter being responsible for necrosis of the subcutaneous tissue. Therapy is synergic and multi-disciplinary, antibiotic with radical and reconstructive surgery. The Authors report a case of Fournier’s gangrene. The discuss about various type of necroting diseases; the different etiological agents. Spreading ways of infectionthrough extermal genitalia,anatomical structures of perneal scrotal region wich are responsible of spreading infection through fixed ways.