The essay intends to analyze the comic fashion phenomenon. If the relationship between fashion and comic strip has been partially crystallized over time, the connection, previously unidirectional, has been overhead by a far more eclectic approach. Leaving aside the notion of comic strip as a trend, this form of art has been adopted also to promote the fashion product, through advertising campaigns with a high visual impact, which, thanks to some of the most important cartoonists’ pencil and wit, besides being real art masterpieces, have realized a strategic package aimed to fix the promoted product into the consumer’s mind. A relationship between comic strip and fashion is lastly focused in the wide cross-breeding that has finally taken place through the cinema.