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Contribuição do tratamento com fármacos Anti-Hipertensores para a Resistência à Insulina na Diabetes Mellitus

Authors: Monteiro, Ana Cláudia do Rosário;

Contribuição do tratamento com fármacos Anti-Hipertensores para a Resistência à Insulina na Diabetes Mellitus

Abstract

A Diabetes Mellitus tipo 2 está muitas vezes associada a Hipertensão Arterial ou Pressão Arterial normal alta e está frequentemente presente nos doentes com Síndrome Metabólica. Os fármacos Anti-Hipertensores têm diferentes efeitos a nível metabólico, existindo evidência científica de que o Sistema Renina-Angiotensina-Aldosterona é fundamental para os mecanismos de Resistência à insulina. O objetivo deste trabalho é compreender os mecanismos dos vários Anti- Hipertensores, e de que forma eles contribuem para o aumento da concentração de insulina e para a resistência por parte dos tecidos à hormona.

Diabetes mellitus type 2 is associated in many times to Hypertension or High-Normal Blood Pressure and occurred frequently in metabolic syndrome patients. Antihypertensive agents have different effects in metabolism. There is evidence that Renin-Angiotensin-Aldosterone System is important for the mechanism of insulin Resistance. The purpose of this work is understand the mechanisms of Antihypertensive agents and how they contribute to the insulin increase tissues resistance to the hormone.

Orientação : Liliana Mendes

Country
Portugal
Related Organizations
Keywords

INSULINA, HIPERTENSÃO, HYPERTENSION, RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM, DIABETES, MESTRADO INTEGRADO EM CIÊNCIAS FARMACÊUTICAS, SISTEMA RENINA- ANGIOTENSINA-ALDOSTERONA, FARMACOLOGIA, INSULIN, PHARMACOLOGY

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citations
The total number of citations received by all articles of the researcher of interest.
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
Green