The aim of this work is to analyse the air traffic development that interested the airport system in Sicily, consisting of the airport of Palermo “Falcone –Borsellino”, the airport of Catania “Fontanarossa” and that one of Trapani-Birgi “Vincenzo Florio”. The analysis of the possible growth of air traffic volume and performance in Sicily was mainly suggested by the growing importance of the Mediterranean region like a new crossroad of the worldwide traffic on the East-West line. It gives a new chance for the development of this area that mustn’t be loosed. Globalization and the migrant flows from South and East towards the Western Europe, makes of the southern Italy a strategic knot for passengers and goods movements. So, new investments and infrastructures improvements that will be realized in this area are a value added not only for the southern Italy but also for the whole country. We have examined the potential demand attraction for passengers and goods movements in the Sicilian airports considered. For a more careful evaluation of the changes occurred into Sicilian air transport system, the research aimed to: § determine their "catchment area" through the evaluation of accessibility (isochrones); § analyse the air traffic data and the existing degree of integration, not only between the airports and the area, but also in terms of demand in the short and in the long period. Finally, we have evaluated the possibility of integration of traffic flows management among the two airports of Palermo and Trapani, in order to analyse if this two airports are complementary rather than competitors.